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Arhgef1 is a hematopoietic-restricted signaling molecule that regulates leukocytemigration and integrin-mediated adhesion.
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Background: Chemokines bind to specific receptors and mediate leukocytemigration to sites of inflammation.
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The acidification did not interfere in leukocytemigration under agar.
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Our results establish a causative role for negative regulators of leukocytemigration in chronic inflammation.
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In addition, Ang-2 exerted a weak stimulatory effect on leukocytemigration in the mouse paw.
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The immune suppressive mechanisms of Tregs include contact-dependent, cytokine secretion and regulation of immunecellmigration.
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Proliferation is necessary for EC-CFU generation; however, colony growth also occurs as a result of leucocytemigration.
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Corticosteroid treatment did not exert a major effect on leucocytemigration, though the doses involved were relatively small.
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Serial studies of leucocytemigration in vivo were carried out in 15 patients with Behçet's syndrome using a skin window technique.
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The innate mechanisms driving (or inhibiting) leukocytetrafficking to allografts remain incompletely understood.
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We now show that aldosterone triggers endothelial cell exocytosis, the first step in leukocytetrafficking.
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Our data show that antibody to host antigens can activate human endothelial cell exocytosis and leukocytetrafficking.
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We hypothesized that endothelial expression of such guidance cues may regulate leukocytetrafficking into the vascular wall during atherogenesis.
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Uveitis was assessed using intravital videomicroscopy, which visualizes leukocytetrafficking within the vasculature and tissue of the iris, and by histology.
Usage of immune cell trafficking in English
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However, the role of S1P receptors in normal immunecelltrafficking is unclear.
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APT reduced intrahepatic platelet accumulation and the frequency of platelet- immune cell interaction, thereby limiting hepatic immunecelltrafficking.
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In conclusion, the DIV-BBBr represents the most realistic in vitro system to study the immunecelltrafficking across the BBB.
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Lymphatic vessels play physiological roles relevant to all medical fields as important regulators of fluid balance, immunecelltrafficking, and immune identity.
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Immunecelltrafficking is orchestrated by a family of small proteins called chemokines.